(SOUNDBITE) (English) NOBEL COMMITTEE SECRETARY THOMAS PERLMANN, SAYING:“The Nobel Assembly at Karolinska Institute has today decided to award the 2016 prize in Physiology or Medicine to Yoshinori Ohsumi for his discoveries of mechanisms for autophagy.”(SOUNDBITE) (English) NOBEL COMMITTEE MEMBER MARIA MASUCCI, SAYING:“There is growing hope that this knowledge will lead to the development of new strategies for the treatment of many human diseases.”(SOUNDBITE) (Japanese) 46-YEAR-OLD COMPANY WORKER, SACHIKO IKEDA, SAYING:“This is impressive! The news this morning said the (Nobel Prize) announcement would be today, and I doubted a Japanese would win for three consecutive years, so this is so wonderful!”(SOUNDBITE) (Japanese) 36-YEAR OLD ACTOR, TAKAHIRO MIYAMOTO, SAYING:“Whenever I hear news like this, I feel this is motivation (for Japan) to work harder especially since there has been many things happening over the past year. Winning is definitely good motivation (for our country).”